Madre de Dios Region Vacations & Trips from $2,147

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Your Madre de Dios Region Vacation

Choose one of our vacation packages to Madre de Dios Region and wander wherever your adventurous soul takes you. Hiking and nature are just a couple of the things you can look forward to in this wonderful destination. Start your trip to Madre de Dios Region by spending a few nights in Tambopata, one of the top cities here. Expedia has hotels, flights and all your other travel needs to help you curate your very own customized Madre de Dios Region vacation today.

The Latest Madre de Dios Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Ecolucerna Lodge Tambopata
Inotawa Lodge
amazonian oropendola tambopata
Tronco Tambopata Adventure

Best Places to Vacation in Madre de Dios Region

1. Escape to Tambopata with a vacation package

Tambopata in the Madre de Dios Region of Peru offers a unique outdoor vacation experience. With its lush jungle and rainforest, it provides the perfect setting for adventure and exploration. Visitors can enjoy activities such as hiking, wildlife spotting, and exploring natural parks. The region is known for its diverse wildlife and stunning natural beauty. Families will find plenty of family-friendly activities to enjoy, and there are also dining options available to satisfy any palate. Whether it's destination activities, tours, or sightseeing, Tambopata offers a memorable outdoor vacation for all.

  • The peak season is from July to September
  • The off-peak season is from November to January
  • Travelers tend to stay 3 days in Tambopata

2. Create memories in Puerto Maldonado with a vacation package

Puerto Maldonado, located in the Madre de Dios Region of Peru, offers a unique outdoor vacation experience. With its lush jungles, majestic rivers, and picturesque lakes, this destination is perfect for nature enthusiasts. Visitors can enjoy boating tours, birdwatching, and exploring the vast rainforests. For those seeking a touch of luxury, there are upscale accommodations available. Puerto Maldonado is a haven for adventure seekers, offering activities such as hunting and sightseeing tours. Immerse yourself in the local atmosphere and experience the beauty of this vibrant city.

  • The peak season is from January to March
  • The off-peak season is from October to December
  • Travelers tend to stay 2 days in Puerto Maldonado

3. Experience Las Piedras with a travel package

Las Piedras in the Madre de Dios Region of Peru offers a stunning atmosphere for outdoor vacations. Immerse yourself in the lush rainforests and explore the vast biodiversity of the Amazon. Go on thrilling adventures like jungle hikes, wildlife spotting, and canoeing along the rivers. Experience the local culture by visiting nearby indigenous communities and learning about their traditions. Stay in eco-lodges and enjoy the tranquility of the surroundings. Whether you're a nature enthusiast or an adventure seeker, Las Piedras offers an unforgettable outdoor vacation experience.

  • Travelers tend to stay 3 days in Las Piedras

4. Find your perfect Manu vacation

Manu, located in the Madre de Dios Region of Peru, offers a unique outdoor vacation experience. The region's geographic affinities make it perfect for natural parks and wildlife conservation. Visitors to Manu can immerse themselves in destination activities, such as guided tours and sightseeing, that allow them to explore the stunning natural beauty of the area. Whether it's trekking through the lush rainforests, spotting exotic wildlife, or visiting indigenous communities, Manu provides an authentic and unforgettable outdoor adventure for travelers from the United States and beyond.

6. Book your ideal Alerta with a vacation package

Inca, Tambopata, in the Madre de Dios Region of Peru, offers a unique and inexpensive vacation experience. Immerse yourself in the lush Amazon rainforest, where you can explore the vibrant biodiversity, encounter exotic wildlife, and witness breathtaking landscapes. Engage in thrilling activities like jungle treks, riverboat tours, and birdwatching. Experience the local culture by visiting indigenous communities, learning about their traditions, and trying traditional cuisine. For an affordable vacation, there are budget-friendly accommodations and local markets to explore. Inca provides an authentic and unforgettable adventure in the heart of the Peruvian Amazon.

5. Enjoy Sandoval with a travel package

Sandoval in Tambopata, Madre de Dios Region, Peru offers a unique and immersive outdoor vacation experience. Nestled within the Amazon rainforest, this region is a haven for nature lovers. Explore the pristine Sandoval Lake, surrounded by lush greenery and home to diverse wildlife such as macaws, monkeys, and giant river otters. Embark on guided jungle treks to discover the rich biodiversity of the area, including vibrant bird species, towering trees, and exotic plants. Immerse yourself in the local culture by visiting nearby indigenous communities and learning about their traditional way of life. Sandoval promises an unforgettable adventure in the heart of the Peruvian Amazon.

Best months to visit Madre de Dios Region

Looking for the best time to visit Madre de Dios Region? Our table will help you. Madre de Dios Region boasts a year-round average temperature of 77.0°F, reaching a peak of 80.4°F in September, its warmest month, and dropping to an average low of 73.9°F in June, the coolest month. The annual rainfall averages 288.1mm, with February experiencing the heaviest showers, while July is the driest month.

Monthcalendar iconTemperature (Fahrenheit)temperature iconRainfallrain iconCloud coveragecloud icon
January77.0Frequent RainMostly Cloudy
February76.3Frequent RainMostly Cloudy
March76.8Frequent RainMostly Cloudy
April76.6Moderate RainMostly Cloudy
May74.8Light RainMostly Sunny
June73.9Light RainMostly Sunny
July74.5No Rain (Dry)Mostly Sunny
August77.5Light RainMostly Sunny
September80.4Light RainMostly Sunny
October79.7Moderate RainMostly Sunny
November78.6Frequent RainMostly Cloudy
December77.4Frequent RainMostly Cloudy

How to save money on a vacation to Madre de Dios Region

  • Combine your flights with hotels or car rentals to save money.
  • Take advantage of Expedia's OneKey program to collect points and save money.
  • Utilize the helpful search filters on Expedia to find the perfect accommodation within your price range.
  • Consider traveling during the off-peak season in Madre de Dios Region (December-February) for better deals.
  • Use the search filter for price limits on Expedia to find a package deal that suits your budget.
  • Discover the best vacation experience for you by using the travel experience filter on Expedia, whether it's a family, romantic, or adventurous getaway.

Madre de Dios Region Essential Information

Language
Spanish
Currency
Peruvian sols
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Padre Aldamiz Intl. Airport (PEM)
Top Sights
Tambopata National Reserve, Sandoval Lake and Manu National Park

Madre de Dios Region Hotel Deals

Libelula Hotel

Libelula Hotel

2 out of 5
Jr Puno No. 429, Tambopata, Madre de Dios
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (17 reviews)
"Great stay, friendly owners and staff."

Reviewed on Jun 22, 2025

Libelula Hotel
Dmilez Hotel

Dmilez Hotel

2.5 out of 5
Psj. Tupac Amaru, Mz. E, Lot 6, A.H.8 de Octubre, Tambopata, Madre de Dios
7.2/10 Good! (26 reviews)
"Air conditioning was cold and very good. Pool is nice. Staff goes above and beyond. Place is clean, Bed is comfortable."

Reviewed on Sep 11, 2025

Dmilez Hotel
IKAM Riverview Amazon Lodge - Asociado Casa Andina

IKAM Riverview Amazon Lodge - Asociado Casa Andina

3 out of 5
Tambopata KM. 7 Otr. Carretera Bajo, Tambopata, Madre de Dios
$202 nightly
The price is $202 total per night from Oct 13 to Oct 14
$202 total
Oct 13 - Oct 14
9/10 Wonderful! (6 reviews)
"Half an hour a at from Puerto Maldonado by boat , the place is lovely, with river view and a feel of the jungle without venturing too far. We felt like we got a good insight into the area, with included excursions on the river and into the jungle. Our guide Yuri, who was with us throughout, was very ..."

Reviewed on Sep 23, 2025

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Madre de Dios Region vacation package cost?
The most affordable Madre de Dios Region package is $2,147, so the trip of your dreams can become a reality — without breaking the bank. Combine flights, hotels and car rentals to build a package that suits you.
How do I get a cheap travel package to Madre de Dios Region?
Combine your bookings with Expedia to save on your next getaway. With over 550 air carriers and 1,000,000 hotel options across the globe, your Madre de Dios Region vacation package can be customized exactly to suit your travel style. With all that extra cash, why not include a few awesome tours and experiences? It's an easy way to unlock even more discounts. That dream vacation to Madre de Dios Region is closer than you thought!
What are the top hotels in Madre de Dios Region?
When it comes to properties in Tambopata, Copasu Hotel and Kapievi Ecovillage are two great options. If you're visiting Las Piedras, Inkaterra Reserva Amazonica and Inkaterra Hacienda Concepcion look forward to welcoming you.
How far in advance should I book my Madre de Dios Region vacation?
Smart travelers will likely want to reserve their seats early. You can normally look up international airfares on Expedia up to a year before your flight. If you're purchasing your ticket at the last minute, don't despair. Low prices sometimes occur in the last weeks prior to departure.
What does an Expedia Madre de Dios Region travel package include?
Expedia has all you need to arrange your Madre de Dios Region trip, but how you structure your package is your call. Select from a combination of hotels, flights and rental cars. Looking for a few activities to keep you on the move? Once you've made your booking, you can add them on too. No matter your style or budget, there's a package to suit your needs.
What should I know before booking a Madre de Dios Region travel package?
Bundling your bookings into a Madre de Dios Region vacation package is the easiest way to organize your trip. Not only that, you'll save big when you combine your hotels, flights and car rentals. Once you've booked, why not add on a day tour or an activity?
Can I choose my airline with a Madre de Dios Region Expedia vacation package?
Definitely. Expedia has over 550 partner airlines to select from all over the world. With so many choices, finding the perfect carrier to whisk you off to Madre de Dios Region will be a breeze.
Does Expedia offer Book Now, Pay Later Madre de Dios Region vacation packages?
Thanks to our partnership with online lender Affirm, you can choose to Book Now, Pay Later. You can tailor your trip with Expedia packages, so why not customize your payment arrangement too?
If I'm not able to travel, can I cancel my Madre de Dios Region vacation package?
Certainly, and we're here to help. You may be able to cancel or change your Madre de Dios Region vacation package at no cost if you booked in the last 24 hours. But you may incur a fee from your hotel, airline or car rental company for older bookings. If life throws you a curveball, visit our Customer Service Portal for more information.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.